The full Midwest Region has been released, and so far, it's the toughest region (also, it was the only one to come out thus far, so, there's that).
1 Kansas v. 16 Lehigh
8 UNLV v. 9 UNI
5 Michigan State v. 12 New Mexico State
4 Maryland v. 13 Houston
6 Tennessee v. 11 San Diego State
3 Georgetown v. 14 Ohio
7 Oklahoma State v.10 Georgia Tech
2 Ohio St. v. 15 UC Santa Barbara
Jokes aside though, this may very well end up being the toughest side of the bracket, with six of the AP top-25: Kansas, Ohio State, Georgetown, Maryland and Michigan State, and Tennessee, as a six-seed.