NFL Week 1 Preview, Prediction: San Francisco 49ers Vs. Seattle Seahawks

San Francisco 49ers (0-0) vs. Seattle Seahawks (0-0)

When: 4:15 p.m. Sunday, FOX

SB Nation 49ers: Niners Nation

SB Nation Seahawks: Field Gulls

Breakdown: Neither of these teams do anything incredibly well but the 49ers enter with a stronger running game and defense. That means the Seahawks will need to get off to a fast start against the 49ers because their offense can't stage a big come back.

Player to Watch: Keep an eye on RB Frank Gore. QB Alex Smith is hardly a top quarterback so the 49ers will put Gore in the driver's seat early and often to control the game. He'll get a lot of touches on Sunday.

Line: 49ers are three-point favorites.

Prediction: Take the 49ers in this game. The Seahawks are missing their starting left tackle and Gore will likely be among the best players on the field. The 49ers should roll in this one.