Beason had been listed as doubtful for Sunday's game due to lingering knee and shoulder issues, and his injury means that rookie first-round pick Luke Kuechly will start for Beason at middle linebacker. Kuechly had been starting at weak side linebacker in Ron Rivera's defense. Gamble is out with a shoulder strain.
The Panthers' offense will also be missing a critical player, with offensive lineman Geoff Hangartner sidelined for Sunday's matchup. The center/guard will miss the game with a knee injury.
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