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Experts are split on this Week 4 matchup.
Five out of seven pickers on CBSSports like Seattle, while two ESPN experts have taken St. Louis. Merril Hoge and Seth Wickersham -- who leads all ESPN and CBS experts with 30 wins -- went with the Rams.
Seattle is 2-1, but some experts may be dubious of the Seahawks' second win, which they picked up on Monday night against the Packers.
Whether or not they should have won that game, Seattle's defense looked strong, sacking Aaron Rodgers eight times in the first half.
St. Louis, meanwhile, is coming off an ugly loss to the Chicago Bears in which it mustered only six points. Quarterback Sam Bradford completed just 18 of 35 passes and threw two interceptions. Running back Steven Jackson was held to 29 yards on 11 carries.
Last season, Seattle won both meetings with St. Louis.