Doug McDermott led the Bluejays with 23 points, scoring 18 points in just 12 minutes of play in the first half. Creighton rode the fast start to a 47-20 lead at the half and forced 10 turnovers while shooting nearly 57 percent from the floor.
McDermott was 5-of-7 from three-point range, with Gregory Echenique adding 16 points and 6 rebounds. Guard Grant Gibbs had 9 assists on the night, as 14 players total contributed on the scoreboard for Creighton in the win.
Saint Joseph's dropped to 4-2 on the season with the loss, with only guard Langston Galloway getting into double digits with 10 points, 3 assists and 4 rebounds on the night. The Hawks shot just 37.7 percent from the floor and were just 7-of-28 from long distance in the game.
The 7-1 Bluejays will face Nebraska on Dec. 6 at 8 p.m. ET.