The game airs at 7 p.m. ET on ESPN.
Kansas comes into the game 6-2, but has dropped two of the last three. Bill Self's group started the season with five straight wins including a 94-83 victory over the Duke Blue Devils in Chicago. However, the Jayhawks have lost to the Villanova Wildcats and Colorado Buffaloes in the last 10 days.
Florida is also sitting at 6-2, and in the midst of perhaps its toughest part of the schedule. Billy Donovan scheduled a brutal non-conference slate, and the Gators find themselves playing the second game of three consecutive contests against ranked opponents. In its last game on Dec. 2, UConn beat Florida 65-64.
Here's a look at the rest of tonight's big games:
Boise State at No. 11 Kentucky (9 p.m. ET, ESPN)
No. 20 Gonzaga at West Virginia (9 p.m. ET, ESPN2)
Oakland at Indiana (7 p.m. ET, ESPN2)