NCAA Tournament Betting: Upset Alert in Round of 64 Bracket Picks

John Rieger-USA TODAY Sports

The upsets always come in March Madness brackets, but which low seeds have the best odds of pulling off the upset? Check out the latest upset picks and predictions, courtesy of the Odds Shark college basketball handicapping staff.

We all know there will be some upsets in the opening round of the NCAA tournament; there always are a few early shockers.

The trick for bettors, though, is to discern those upsets before they become reality, and get some money down on the appropriate sides.

Which games might be ripe for surprise Thursday? Here's a quick look at a few candidates along with the odds to win March Madness, courtesy of

Colorado State went 11-5 in what was a tough Mountain West Conference this season, owns 25 victories overall, and of its eight defeats seven came against teams that made the NCAA tournament.

The Rams' opponents for Thursday, the Missouri Tigers, went 11-7 in what was a weak SEC this season. And Mizzou lost five games this year to teams that missed the tournament.

Missouri is favored by three points over Colorado State, but many are wondering if the books don't have the chalk listed next to the wrong team. [ More March Madness upset predictions ]

Belmont went 16-2 in the Ohio Valley Conference this season, won the conference tournament, beat Stanford and lost a (reasonable) close game to VCU. Of the Bruins' six defeats this season at least four could be called close.

Belmont throws it in the hole to the tune of 77 PPG, shoots 49 percent from the floor and hassles foes into shooting just 41 percent.

The Bruins are getting 4.5 points Thursday from an Arizona team that's only 5-5 over its last 10 games. Belmont is also playing in the NCAA tournament for the third straight year, having lost to Wisconsin and Georgetown the previous two seasons.

Might the Bruins have enough Big Dance experience to finally pull an upset? The super-computer is picking Belmont to win here.

Other potential upsets for Thursday would have to include Davidson, which enters the tournament with a 17-game winning streak, as four-point underdogs against Marquette; Bucknell, which has lost just three games since Christmas by a combined six points, as four-point underdogs against Butler; and Oregon, which just won the Pac-12 tournament, as two-point underdogs against Oklahoma State.

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