Elena Delle Donne looks to keep her dominant Delaware career alive with a performance in the Sweet 16, while usual suspects Connecticut and Stanford look to keep moving on after pounding their Round of 32 opponents.
There are four games on Saturday, and unlike previous rounds, every game will be broadcast from start to finish on ESPN or ESPN2. That means a whole lot of hoops on TV, as the action kicks off at noon and keeps going into the night.
Here's a look at each game:
12 p.m. ET: No. 6 Delaware vs. No. 2 Kentucky, at Bridgeport, CT, ESPN
Delle Donne has gotten the Blue Hens making school history after posting 33 points to knock off No. 3 North Carolina in a raucous Round of 32 game in front of Joe Biden. But Kentucky has a star too, A'Dia Mathies, who had 34 points despite a stomach virus in their game against Dayton.
2 p.m. ET: No. 4 Maryland vs. No. 1 UConn, at Bridgeport, CT, ESPN
It's almost unfair that a team as elite as Geno Auriemma's gets to play so close to home, but those are the breaks. The Huskies have won their first two games by a combined 101 points, and now play Maryland, who they already beat, 63-48, earlier in the year.
9 p.m. ET: No. 4 Georgia vs. No. 1 Stanford, at Spokane, WA, ESPN
The Bulldogs survived a huge run from Iowa State in their Round of 32 game, holding on behind 20 points from Shacobia Barbee. Now they have to face off against the only team in the country who has beaten Brittney Griner and Baylor. The Cardinal stomped Michigan by 33 to reach the Sweet 16.
11:30 p.m. ET: No. 6 Tigers vs. No. 2 Cal, at Spokane, WA, ESPN2
Adrienne Webb had a career-high 29 points to power the Lady Tigers past No. 3 Penn State in their last game, while Cal struggled with 10-seeded South Florida. They were up three, fouled a shooter with under a second left to give the Bulls three free throws to tie, which they sank, sending the game to overtime. They'd eventually win, but it wasn't a good look for a squad considered one of the nation's elites.