Russ Smith scored 12 points to pace the Cardinals, who overcame significant adversity to put together a strong run to close the opening half.
Louisville's Kevin Ware suffered a gruesome injury at the 6:33 mark while trying to defend Tyler Thornton's three-pointer, resulting in a delay of several minutes. Duke scored six of the next eight points when play resumed to take a three-point advantage, but Louisville answered back with a similar stretch to retake the lead on Smith's pair of free throws with 2:13 remaining. Smith made two more free throw attempts at the end of the half to extend the Cardinals' lead to three.
Mason Plumlee scored nine points, grabbed six rebounds and was responsible for this dunk:
The Blue Devils stayed within striking distance of the Cardinals despite losing Ryan Kelly for a majority of the half due to foul trouble.