March Madness betting lines open with Virginia, Arizona biggest favorites

Dale Zanine-USA TODAY Sports

Top seeds opened as favorites of 20 points or more as the March Madness betting lines were posted this week. Florida and Wichita State could lay even more points when the play-in games are over.

Virginia and Arizona were favored by 20 and 21 points respectively as odds were posted for the 2014 bracket this week. And fellow No. 1 seeds Florida and Wichita State could open laying even more points, but oddsmakers must await the results of the First Four play-in games before posting their numbers.

It's a similar story each March, as high-profile top seeds are given a pass in the first round. No 16 seed has ever beaten a No. 1, and No. 2s rarely lose to No. 15s. But factor in the point spread and these opening matches become intriguing for bettors.

Top seeds were just 1-3 ATS last year, and No. 5 seeds suffered the same fate against No. 12 seeds.

Check out the opening lines courtesy of OddsShark.com and visit their free searchable March Madness database to research the history of every team and every seed matchup.

*First Four games go Tuesday/Wednesday
Mount St. Mary's +2.5 141.5o
Albany -2.5 141.5u
Matchup Dayton Arena
Preview 6:40 PM
North Carolina State +2 142o
Xavier -2 142u
Matchup Dayton Arena
Preview 9:10 PM
Cal Poly -2.5 130o
Texas Southern +2.5 130u
Matchup Dayton Arena
Preview 6:40 PM
Iowa -1.5 142.5o
Tennessee +1.5 142.5u
Matchup Dayton Arena
Preview 9:10 PM
Dayton +6 131.5o
Ohio State -6 131.5u
Matchup First Niagara Center
Preview 12:15 PM
American +13.5 122.5o
Wisconsin -13.5 122.5u
Matchup Bradley Center
Preview 12:40 PM
Pittsburgh -5.5 128.5o
Colorado +5.5 128.5u
Matchup Amway Center
Preview 1:40 PM
Harvard +2.5 122.5o
Cincinnati -2.5 122.5u
Matchup Spokane Arena
Preview 2:10 PM
Western Michigan +13 128o
Syracuse -13 128u
Matchup First Niagara Center
Preview 2:45 PM
BYU +5.5 158o
Oregon -5.5 158u
Matchup Bradley Center
Preview 3:10 PM
Delaware +14 149.5o
Michigan State -14 149.5u
Matchup Spokane Arena
Preview 4:40 PM
Saint Joseph's +4.5 130o
Connecticut -4.5 130u
Matchup First Niagara Center
Preview 6:55 PM
Wofford +16 126.5o
Michigan -16 126.5u
Matchup Bradley Center
Preview 7:10 PM
North Dakota State +3.5 150o
Oklahoma -3.5 150u
Matchup Spokane Arena
Preview 7:27 PM
Wisc-Milwaukee +16.5 140o
Villanova -16.5 140u
Matchup First Niagara Center
Preview 9:25 PM
Arizona State +1.5 142.5o
Texas -1.5 142.5u
Matchup Bradley Center
Preview 9:40 PM
Manhattan +16 142.5o
Louisville -16 142.5u
Matchup Amway Center
Preview 9:50 PM
New Mexico State +7 128o
San Diego State -7 128u
Matchup Spokane Arena
Preview 9:57 PM
Mercer +13 141o
Duke -13 141u
Matchup PNC Arena
Preview 12:15 PM
Nebraska +3.5 130.5o
Baylor -3.5 130.5u
Matchup AT&T Center
Preview 12:40 PM
Stanford +3.5 137o
New Mexico -3.5 137u
Matchup Scottrade Center
Preview 1:40 PM
Weber State +20 127o
Arizona -20 127u
Matchup Viejas Arena
Preview 2:10 PM
Louisiana-Lafayette +14 154.5o
Creighton -14 154.5u
Matchup AT&T Center
Preview 3:10 PM
Eastern Kentucky +15 146o
Kansas -15 146u
Matchup Scottrade Center
Preview 4:10 PM
Oklahoma State -2 139o
Gonzaga +2 139u
Matchup Viejas Arena
Preview 4:40 PM
George Washington +3 142.5o
Memphis -3 142.5u
Matchup PNC Arena
Preview 6:55 PM
Providence +4 143o
North Carolina -4 143u
Matchup AT&T Center
Preview 7:20 PM
Stephen F. Austin +6.5 137o
Virginia Commonwealth -6.5 137u
Matchup Viejas Arena
Preview 7:27 PM
Coastal Carolina +21 121.5o
Virginia -21 121.5u
Matchup PNC Arena
Preview 9:25 PM
Kansas State +5 132.5o
Kentucky -5 132.5u
Matchup Scottrade Center
Preview 9:40 PM
North Carolina Central +8.5 143.5o
Iowa State -8.5 143.5u
Matchup AT&T Center
Preview 9:50 PM
Tulsa +9.5 146o
UCLA -9.5 146u
Matchup Viejas Arena
Preview 9:57 PM

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