Rashard Mendenhall is still nursing a knee injury, but there's no reason to believe he won't be at full strength or close to it. The Pittsburgh Steelers running back had full participation this week and is listed as probable heading into their game against the Arizona Cardinals.
Mednenhall missed Week 5 against the Tennessee Titans, a game in which Jonathan Dwyer had a big impact, but he returned to the No. 1 RB role against the Jacksonville Jaguars last week. Mendenhall picked up 146 yards rushing on 23 carries and scored a touchdown, looking nothing like a player who was nursing a knee injury.
Isaac Redman has been effective this year and has taken some of the carries away from Mendenhall even when he's been healthy, but there's no reason to believe Mendenhall won't get 20+ touches against the Cardinals.