Manningham has just 278 yards and one TD on the season. He has been targeted just 37 times and has not cleared 72 receiving yards in any of his seven games.
Fantasy Impact: Manningham hasn't done much this year and the 49ers are wise not to get him the ball too much. While that might sound like Mario-bashing, the 49ers are built on defense and shortening the game by running the ball should help their chances to win.
He has minimal upside and shouldn't even be owned in 16-team leagues.