Locker has played in just seven games this year due to his shoulder problems and has just 1,473 yards passing with eight TDs and seven interceptions.
Fantasy Impact: Locker really struggled last week against the Texans and completed 21-of-45 attempts for 309 yards. Obviously, the Texans D is much better than the Colts and Locker should have more success on Sunday.
Locker has his receiver healthy with Kenny Britt in his best shape in a while and the Titans are expecting them to get on the same page. Britt is a high-upside WR3 this week and Locker is a high-end QB2 in two-QB leagues. He carries some risk, though.