Wayne was targeted nine times by Luck against Pittsburgh, catching six of those passes for 74 yards. Austin Collie exited the game in the first quarter, and Wayne saw the majority of his targets after this point.
Analysis: Most critics are calling 2012 to be the year Wayne experiences major regression. However, if Collie misses a significant amount of time, someone is going to have to step up and be the go-to-guy for Luck. Wayne showed on Sunday night that he is fully capable of handling the No. 1 receiver workload in Indianapolis.
Fantasy owners will want to monitor this situation closely. Without Collie in the lineup, Wayne can be a threat to put up strong numbers. In their preseason game together, Collie received five targets, while Wayne only had Luck look his way once. Tonight, though, it was a completely different story with concussion issues rearing its ugly head with Collie again.