He's going to play; this is just more of the Patriots up to their usual tricks on the injury report. He was targeted nine times in Week 5, catching five balls for 55 yards in the loss to the Bengals. Cincy shut down the Patriots offense, so his line isn't as bad as you'd think.
The Patriots really have lacked a go-to guy for much of the season. Rob Gronkowski is still hurt and Amendola's groin has really limited him. Their young receivers of Kenbrell Thompkins and Aaron Dobson haven't been able to haul in passes for much of the season, and it's cost Tom Brady some of his usually efficient numbers.
Fantasy impact: If you're in a PPR league, you kind of have to play Amendola. The Saints should be able to put up quite a few points. The Saints are surprisingly 21st in YPA allowed, but they had a couple of outliers to help that ranking.