Jones, with 349 receiving yards and two touchdowns on 20 catches this season, is the second premium Packers' pass-catcher who is out for the game, joining the now-on-injured-reserve Randall Cobb.
Fantasy impact: With Jones out, the Packers will likely lean more heavily on established stars Jordy Nelson and Jermichael Finley against a strong Browns pass defense, including top-flight cornerback Joe Haden.
Assuming Haden matches up with Nelson, second-year receiver Jarrett Boykin could theoretically see some decent value as well, as the Packers tend to have a way of creating receivers when the situation necessitates it.
Jones wasn't officially deemed inactive until Sunday, indicating he was likely close to being able to go. Assuming that's true, there is reason to think he'll be back at it for the Packers next game, next Sunday night against Minnesota.