Spiller has been dealing with an ankle injury but said it felt better than he anticipated on Monday. With the Bills playing on a short week, Spiller's progress will be important to monitor.
Fantasy spin: Spiller has been less than impressive for fantasy owners that rolled the dice on him in the first round. He has 230 rushing yards this season and hasn't scored a single touchdown in four games.
It's not time for Spiller owners to panic just yet, but this is not the output they were hoping for. If he doesn't bounce back from this ankle injury, the season could get away from him in a hurry. Spiller missing Thursday night's game may be the best thing for him longterm.