| Year | Team | G | GS | W | L | SV | CG | SHO | IP | H | R | ER | HR | BB | K | ERA | WHIP |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2001 | 0 | 9 | 9 | 4 | 2 | 0 | 0 | 0 | 47 | 48 | 16 | 12 | 2 | 10 | 42 | 2.30 | 1.23 |
| 2002 | 0 | 25 | 25 | 10 | 7 | 0 | 1 | 0 | 152.1 | 159 | 61 | 56 | 9 | 46 | 100 | 3.31 | 1.35 |
| 2003 | 0 | 25 | 22 | 15 | 5 | 0 | 2 | 1 | 147.2 | 140 | 60 | 54 | 9 | 29 | 83 | 3.29 | 1.14 |
| 2004 | 0 | 28 | 28 | 13 | 10 | 0 | 1 | 0 | 176 | 155 | 89 | 76 | 12 | 56 | 185 | 3.89 | 1.20 |
| 2005 | 0 | 13 | 12 | 4 | 4 | 1 | 0 | 0 | 65.2 | 53 | 25 | 22 | 6 | 12 | 57 | 3.02 | .990 |
| 2006 | 0 | 21 | 17 | 8 | 4 | 0 | 0 | 0 | 92.2 | 95 | 51 | 50 | 15 | 43 | 76 | 4.86 | 1.49 |
| 2007 | 0 | 31 | 2 | 3 | 5 | 2 | 0 | 0 | 52.1 | 48 | 39 | 32 | 9 | 25 | 56 | 5.50 | 1.39 |
| 2009 | 0 | 3 | 1 | 0 | 1 | 0 | 0 | 0 | 7 | 13 | 8 | 8 | 2 | 3 | 4 | 10.29 | 2.29 |
| career | Total | 28 | 14 | 5 | 6 | 0 | 0 | 0 | 86.2 | 107 | 63 | 58 | 25 | 31 | 72 | 6.02 | 1.59 |
To this Astacio page
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| August 31, 2009 | Signed by the Chicago Cubs to a minor league contract. |
| November 3, 2007 | Opted for minor league free agency. |
| March 31, 2007 | Designated for assignment by the Texas Rangers. |
| March 26, 2007 | Claimed off waivers from the Houston Astros. |
| May 12, 2006 | Optioned to Round Rock (AAA). |
| April 14, 2006 | Recalled from Round Rock (AAA). |
| March 26, 2006 | Optioned to Round Rock (AAA). |
| February 22, 2006 | Re-signed by the Houston Astros to a one-year contract. |
| October 12, 2005 | Added to the NLCS playoff roster. |
| October 5, 2005 | Did not make the playoff roster. |
| July 27, 2005 | Recalled from Round Rock (AAA). |
| July 19, 2005 | Optioned to Round Rock (AAA). |
| July 14, 2005 | Recalled from Round Rock (AAA). |
| July 3, 2005 | Optioned to Round Rock (AAA). |
| July 2, 2005 | Recalled from Round Rock (AAA). |
| May 31, 2005 | Optioned to Round Rock (AAA). |
| May 3, 2005 | Recalled from Round Rock (AAA). |
| April 2, 2005 | Optioned to Round Rock (AAA). |
| February 22, 2005 | Re-signed by the Houston Astros to a one-year contract. |
| March 18, 2004 | Optioned to New Orleans (AAA). |
| February 28, 2004 | Re-signed by the Houston Astros to a one-year contract. |
| November 19, 2003 | Added to the 40-man roster. |
| November 3, 2003 | Acquired from the Philadelphia Phillies. |
| August 31, 2009 | Signed by the Chicago Cubs to a minor league contract. |
| March 26, 2007 | Claimed off waivers by the Texas Rangers from the Houston Astros. |
| November 3, 2003 | Houston Astros traded Billy Wagner to the Philadelphia Phillies for Brandon Duckworth, Taylor Buchholz and Ezequiel Astacio. |
| February 22, 1998 | Signed as a non-drafted free agent by the Philadelphia Phillies. |
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