NFL Odds And Lines Week 10: Giants Vs. 49ers

LANDOVER, MD - NOVEMBER 6: Alex Smith #11 of the San Francisco 49ers heads off the field after the game against the Washington Redskins at FedEx Field on November 6, 2011 in Landover, Maryland. (Photo by Scott Cunningham/Getty Images)

The New York Giants and San Francisco 49ers face off in one of Week 10's premier matchups, and 49ers opened as 3.5-point favorites.

Two of the hottest teams in the NFC will show down in Week 10 for a potential preview of a rematch in the playoffs when the New York Giants travel west to visit the San Francisco 49ers. The Giants are coming off a huge comeback victory over the New England Patriots, while the 49ers have the second-best record in football. The folks at Odds Shark believe in the power of home field advantage, though, and have the Niners as 3.5-point favorites.

The Giants have, as is their habit, been maddeningly inconsistent this year. While they're capable of having games like last week's they've also lost to the two-win Seattle Seahawks and almost became the Miami Dolphins' first victory in Week 8. The 49ers, on the other hand, have been the models of consistency, beating teams like the Detroit Lions, the Cincinnati Bengals and the Philadelphia Eagles along their way to a 7-1 record.

Fore more info on these two teams, visit Giants blog Big Blue View, 49ers blog Niners Nation, SB Nation New York and SB Nation Bay Area.

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