Patrick Willis #52 of the San Francisco 49ers celebrates in front of John Skelton #19 of the Arizona Cardinals after the San Francisco 49ers recovered a fumble at Candlestick Park in San Francisco, California. San Fransisco plays the St. Louis Rams in Week 13. (Photo by Ezra Shaw/Getty Images)
The San Fransisco 49ers are predictably massive favorites over the St. Louis Rams
Despite their loss in the Harbaugh Bowl on Thanksgiving, the San Francisco 49ers look like they're headed towards the second seed in the NFC, thanks in part to a very weak division. One of the members of that weak division is the St. Louis Rams, who have to go away to Candlestick Park this weekend. Unsurprisingly, the 49ers are very heavily favored. They opened as 13 1/2 point favorites according to Odds Shark.
The line is holding steady for the most part, with some movement in both directions at different sports books. This implies that the line was a pretty good one in the first place, but your smart money is probably still on the 49ers. They're 5-0-1 against the spread at home, while the Rams are 1-4 against the spread on the road this season.