The St. Louis Rams will take on the New York Giants at MetLife Stadium, potentially without the help of do-everything back Steven Jackson. Jackson will be a game time decision after injuring his quad during the Rams' blowout Week 1 loss to the Philadelphia Eagles. With Danny Amendola doubtful with an elbow injury, the Rams could be severely shorthanded against a tough Giants defense.
Of course, the Giants have their own injury issues, starting with top wideout Hakeem Nicks. Nicks insists he will play Monday despite a bruised left knee, but there's still a chance he could be limited. If you are worried about your fantasy team, expect Mario Manningham to pick up any slack left by Nicks. The Giants will also be without defensive end Osi Umenyiora due to a knee injury, which should help the Rams breathe a little easier Monday night.
Considering how lackluster both teams looked in their season openers it's hard to say that either looks like a clear-cut favorite. The Giants do enter as 4.5-point favorites, though at this point the "under" on the 43-point over/under looks like a safer bet.
Game Date/Time: Monday, September 19; 8:30pm ET
Location: MetLife Stadium, East Rutherford, NJ
TV Distribution Map: The506.com
Rams: WXOS 101.1 FM
Giants: WCBS 880 AM