The Buffalo Bills held a 21-0 lead after the first quarter against the New England Patriots in Week 17. And then the Patriots ran off 49 unanswered points to win 49-21. Such is life in 2011 for the Bills.
Tom Brady, as ever, spear-headed the Patriots' offensive assault. Brady threw for 338 yards and three touchdowns, passing Dan Marino for second place on the all-time list for passing yards in a single season, and New England poured it on in the second half, with 35 points to the Bills' zero.
As for Buffalo, an early spurt led by Ryan Fitzpatrick was simply not enough. Fitzpatrick threw for more than 200 yards in the first half, but finished with just 307 yards and four interceptions.
The Patriots secured the No. 1 seed in the AFC with the win, finishing at 13-3 on the year, and will have home field advantage throughout the AFC playoffs. The Bills finish 2011 at 6-10.