Merriman appeared in five games for the Bills last season, recording nine tackles and one sack.
Bills defensive end Mark Anderson (knee) and offensive tackle Cordy Glenn (ankle) have been declared inactive for the game. Defensive end Mario Williams will play against Tennessee after being listed as probable for the entire week.
The Tennessee Titans declared quarterback Jake Locker (shoulder) and running back Javon Ringer (knee) inactive for Sunday's tilt with the Bills.
The complete inactive lists for both teams are as follows:
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