Mankins is considered one of the toughest players in the NFL. Last season, Mankins tore his ACL in September and did not miss a single game, according to ESPN's Adam Schefter.
Mankins, 30, is a four-time Pro Bowler. In his eight-year career, Mankins has started 109 games -- including all 16 in his rookie season in 2005.
The 6'4 California native was a first-round draft pick in 2005. He was drafted 32nd overall. Mankins was a first-team All-Pro in 2010.
The Patriots hold a 24-17 lead over the Bills in the third quarter. With more than eight minutes left in the quarter, the Patriots are in Bills territory.