McCoy was injured on a helmet-to-helmet hit Sunday.
According to the Eagles' official website, McCoy has a concussion.
Before his injury, McCoy had 45 yards and a fumble on 15 carries. McCoy was the team's leading receiver, catching six passes for 67 yards.
McCoy came into the season considered one of the top three backs in the NFL, but the fourth-year man out of Pittsburgh hasn't quite lived up to the hype. In nine games, McCoy has racked up 705 yards and two touchdowns on 162 carries.
The numbers are good, but don't match up to his 2011 season. Last season, McCoy had 1,309 rushing yards and 20 total touchdowns in 15 games for the Eagles.
With the loss Sunday, the Eagles fell to 3-7 and have lost six in a row.