Denver is coming off of a 30-23 victory over the San Diego Chargers last weekend. The Broncos didn't cover in that game, and that is usually the case in contests in which they're favored by more than eight points, going 0-10 against the spread in those situations.
The Chiefs hope to break a string of poor play at home. They are 0-5 overall, and 1-4 against the spread, at Arrowhead Stadium this season.
The over/under is set at 44. The Broncos and their opponents have eclipsed that number in all but one of their games this season, while the Chiefs and their foes have gone over that total in six out of 10 games. However, in four out of their last six, the Chiefs and their opponents have scored 42 points or less.
Kickoff between Denver and Kansas City is slated for 1 p.m. ET on Sunday. The game will be broadcast on CBS.