Jacksonville beat the Tennessee Titans in Week 12, 24-19, ending an ugly seven-game losing streak and moving their overall record to 2-9. Chad Henne performed well for the second straight week, completing 17-of-26 passes for 261 yards with two scores and one interceptions.
Buffalo sits at 4-7 and is coming off a 20-13 defeat at the hands of Andrew Luck and the Indianapolis Colts. C.J. Spiller had an excellent game on the ground, but Ryan Fitzpatrick struggled throwing the ball.
Because of the struggles of both teams this season, this game is somewhat of a toss-up, although most experts are sticking with the home team. Five of eight experts at CBS Sports have picked the Bills, as have two of three at Yahoo! Sports. SB Nation's Joel Thorman is also picking a Bills victory.