The Seahawks are undefeated at home this season, as usual, and are hoping to build off a big 23-17 overtime road win against the Chicago Bears. Sidney Rice caught the winning touchdown just as he was apparently being knocked unconscious while crossing the goal line. Rookie quarterback Russell Wilson has shined at times this season and has not committed a turnover since Oct. 28 against the Detroit Lions.
The Cardinals, meanwhile, boast one of the NFL's lowest-scoring offenses that does little to complement a solid and aggressive defense. Arizona has lost eight straight games after starting the season 4-0 and now face continuing questions at quarterback. John Skelton has been named the starter under center against Seattle after Ryan Lindley's disastrous performance against the New York Jets.
The Seahawks are just one-point favorites, however, as Wilson will be facing a strong Cardinals defense. The over/under is set at 41 points, despite neither team averaging more than 21 points a game. The Cardinals beat the Seahawks, 20-16, in the first game of the season.
Kickoff is set for 4:25 p.m. ET, with coverage on Fox.