GLENDALE, AZ - SEPTEMBER 09: Quarterback John Skelton #19 of the Arizona Cardinals is carted off the field after an injury during the season opener against the Seattle Seahawks at the University of Phoenix Stadium on September 9, 2012 in Glendale, Arizona. The Carindals defeated the Seahawks 20-16. (Photo by Christian Petersen/Getty Images)
The Cardinals, Rams and Seahawks had important players all suffer potentially major injuries on Sunday.
The NFC West had a solid day on Sunday, with the San Francisco 49ers defeating the Green Bay Packers, the St. Louis Rams sticking with the Detroit Lions and the Arizona Cardinals and Seattle Seahawks taking each other down to the wire. But all was far from well on the injury front.
Let's start with the one team that escaped Sunday's game without a major injury. The Niners entered their Week 1 matchup without key offensive role players Ted Ginn and Brandon Jacobs but left Green Bay without adding anyone notable to the injury report. The division's three other teams, though, were not as lucky.
In Detroit, Rams left tackle Rodger Saffold was removed from the field in a stretcher and later taken to a hospital with a neck injury. St. Louis Rams head coach Jeff Fisher told reporters after the game that Saffold was "conscious" and "alert," but it's fair to assume that he is out indefinitely.
In Arizona, Cardinals' starting quarterback John Skelton was carted off the field with an ankle injury. The severity of the injury has yet to be revealed, but Kevin Kolb, who threw the game-winning touchdown pass on Sunday, may have to start in at least the next game. Also in the desert, Seahawks' left tackle Russell Okung had to leave the game on Seattle's last drive after injuring his knee. The Seahawks have yet to elaborate on the severity of the injury.
For more on the Niners, visit Niners Nation. For more on the Rams, check out Turf Show Times. For more on the Cardinals, head over to Revenge of the Birds and for more on the Seahawks swing by Field Gulls. For more news, notes and analysis from around the league, stick with SB Nation's NFL news hub.



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