When the Dallas Cowboys kick off their 2012 season against the defending Super Bowl champion New York Giants on Wednesday night, they will do so without defensive tackle Jay Ratliff.

The four-time Pro Bowler has been ruled out for Wednesday's game and is still recovering from a high ankle sprain suffered during the third preseason game. Against the St. Louis Rams Ratliff hurt the ankle and the injury may sideline him for next week's game as well.

Joining Ratliff on the injury report is tight end Jason Witten, who is doubtful to play with a lacerated spleen. Witten, a seven-time Pro Bowler and five-time All-Pro, returned to practice on Sunday for the first time since the injury suffered in the team's first preseason game against the Oakland Raiders.

Rounding out the injury report for the Cowboys are cornerback Michael Jenkins and special teamer Danny McCray, listed as questionable and doubtful, respectively.

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