The Cardinals are currently one-point favorites, according to OddsShark.com. With the narrow point spread, Arizona likely enters the game as a favorite only because they are playing at University of Phoenix Stadium.
The two teams split their meetings last season, with Arizona winning 23-20 at home. The Cardinals are 6-4 in their last 10 games against the Seahawks and are 6-4 against the spread over that same period.
Both teams are breaking in a new starting quarterback after training-camp battles for the position. Russell Wilson will be making his first NFL start for Seattle while John Skelton will start for the Cardinals. The current over/under for the game is set at 41.5.
Both teams were strong against the spread last season, with Seattle going 10-5-1 and Arizona going 9-7.
For more on the Seahawks, check out Field Gulls and SB Nation Seattle. For more on the Cardinals, check out SB Nation Arizona and the SB Nation blog Revenge Of The Birds. Also visit SB Nation's NFL hub for more news from around the league.