Jones was seen favoring his leg as he limped off the field. He had one reception for 10 yards before exiting the game.
Jarrett Boykin, who replaced Jones, is a second-year veteran who entered the game with five career catches.
Jones, in his seventh year, has been a major factor in the Packers' passing attack this season, providing Aaron Rodgers with a reliable set of hands after the departure of Greg Jennings in the offseason. Jones has 19 catches for 339 yards and two touchdowns this season.
His biggest performance came in a Week 2 win over the Redskins, where he had 11 catches on 12 targets and piled up 178 yards. He also went over the 100-yard mark last week in a win over Detroit, going for 127 yards and a touchdown.
UPDATE: The Packers have announced that Jones is out for the rest of the game:
In addition to Jones, the Packers are now also without star wideout Randall Cobb, who took a nasty shot to the lower leg just before the half in Baltimore. More on Cobb's injury here.