With the Rams playing on the road, most aren't too confident in St. Louis' ability to pull off the upset. The entire crew at SB Nation picked the 49ers to win the game, and few are disagreeing with the selection.
The vast majority of those polled over at ESPN also thinks the 49ers are going to win the game, and NFL.com picked San Francisco to win as well.
However, things change when the spread is involved. CBS Sports has the spread at 7.5 points in favor of the 49ers, so nearly the entire CBS team picked the Rams to cover that point spread.
While most consider the 49ers the favorite to win the game, based on the way the two teams are playing, it's clear most think this will be a fairly close game between the two sides.