After missing four games because of an MCL injury, San Francisco guard Mike Iupati will be back in the lineup on Monday. Iupati is active for San Francisco and will start at guard.
Adam Snyder filled in for Iupati, but will now revert to a backup role. Although San Francisco will have a healthy offensive line, the 49ers will be without Mario Manningham, who is inactive. Manningham missed practice this week because of illness and a knee injury.
The Falcons will be without linebacker Sean Weatherspoon, who is inactive because of a knee injury. Weatherspoon did not practice during the week. Tony Gonzalez, however, is active and will play despite being limited in practice because of a lingering toe injury.
Here are the complete inactive lists for both teams.
TE Derek Carrier, LB Nick Moody, OG Ryan Seymour, DT Quinton Dial, OG Joe Looney, WR Mario Manningham, WR Jon Baldwin
WR Darius Johnson, RB Josh Vaughan, S Zeke Motta, LB Sean Weatherspoon, OT Terren Jones, OT Sean Locklear, DT Travian Robertson