Buffalo looked very good in its opener, but ultimately couldn't beat the New England Patriots, losing 23-21. E.J. Manuel wasn't spectacular, but he certainly impressed by throwing for two touchdowns and completing 18 of 27 passes. The Bills also rushed for 136 yards to control the ball at times, with Fred Jackson's 67 yards leading the way.
Carolina also played a solid game in Week 1, especially on defense. The Panthers held down Russell Wilson and the Seattle Seahawks to 12 points, holding a lead well into the fourth quarter before giving it up.
Cam Newton couldn't get much going with Richard Sherman and co. on the other side, racking up only 125 yards.
Time: 1 p.m.
Radio: CAR - 1110 AM WBT and SEA - 710 ESPN