Andrew Luck shook off a slow start to play sensationally in the second half. He finished with 260 passing yards, two touchdowns and one interception. Luck got support from Reggie Wayne and Coby Fleener, who combined for 177 receiving yards and two touchdowns.
The Jaguars find themselves at 0-4 this season. Blaine Gabbert returned to action this week, but his play might have warranted holding him out. Gabbert finished with just 149 passing yards, throwing two interceptions, including a costly pick-six. He finished with a quarterback rating of 24.1, and it remains to be seen if his struggles could prompt another change at the position.
Neither team had success running the ball, as both Trent Richardson and Maurice Jones-Drew struggled. The two running backs combined for fewer than 90 yards as Donald Brown's 65 yards led the game in rushing.
Fantasy studs and duds
Andrew Luck and Reggie Wayne were both sensational this week. Wayne finished with 100 yards receiving and a touchdown.
Maurice Jones-Drew had a terrible day, averaging just 1.8 yards per carry to finish with 23 yards on the day.
Did they cover?
The Indianapolis Colts were 8.5-point favorites, according to OddsShark. Their big victory means they covered easily.
Oct. 6: Indianapolis vs. Seattle
Oct. 6: Jacksonville vs. St. Louis