Buffalo Bills running back C.J. Spiller suffered an ankle injury in Sunday's game against the Baltimore Ravens. He limped off the field during the third quarter after a botched handoff with E.J. Manuel and needed attendance from trainers. His return is questionable.
Spiller suffered a knee injury in last week's loss to the New York Jets. He went to the locker room and did not return. The team later called it a quad injury, but it wasn't considered serious. He had a full week of practice and got the start in Week 4.
Before the injury, Spiller had 21 carries for 65 yards. Fred Jackson entered the game in his place. Jackson recorded 109 total yards from scrimmage while replacing Spiller last week. He has six carries for 36 yards and a touchdown in limited time against the Ravens, but now figures to see more touches with Spiller out again.