The Colts come into the contest as a small favorite, laying 2.5 points against Kansas City, according to Oddsshark.com.
Indianapolis comes in with plenty of confidence, riding a three-game winning streak including a 23-7 pounding of the Chiefs two weeks ago in Arrowhead Stadium. Conversely, Kansas City lost its final two games, albeit the last loss coming with all backups almost beating the San Diego Chargers, 27-24.
The Colts and Chiefs are both 11-5, but got there in different ways. Kansas City relies heavily on running back Jamaal Charles, who led the league with 19 touchdowns scored. Indianapolis is riding the golden arm of Andrew Luck, who only threw for 3,822 yards but did so with almost no real threats once Reggie Wayne went down with a torn ACL.