The bad news for Packers bettors is that he won't play when Green Bay kicks off Thanksgiving Day NFL festivities at Detroit.
Matt Flynn will start again as the Packers try to end a four-game ATS losing skid as a road underdog.
Green Bay opened as 3.5-point underdogs but the number had swollen to -7 by Wednesday at most sportsbooks monitored by OddsShark.com.
In a normal setting, bettors would expect to see the Packers favored here. They have dominated the Lions over the years with a 12-3 ATS streak and Detroit has struggled to a 1-6 ATS in seven recent home games against its NFC North foes.
And the absence of Rodgers is the terrible-tasting icing on a disgusting cake for Lambeau fans.
"We tend to give the advantage to established teams in a short week, which means playing against a team working in a new quarterback," said Jack Randall of OddsShark.com. "The NFL odds could continue to climb in this game as the Lions are motivated and the Packers just seem to be holding on and praying for a speedy Rodgers recovery."
Packers vs Lions Trends (based on closing lines from 5Dimes)
Packers are 12-3 ATS past 15 games vs Lions
Lions are 1-6 ATS past seven at home to Packers
UNDER is 10-3 past 13 Packers divisional road games
Packers are 0-4 SU & ATS as road underdog
OVER is 9-2 past 11 Detroit games when favored at home