In a week full of huge spreads, the closest game on paper appears to be the San Francisco 49ers at Arizona Cardinals game, which many bookmakers have listed as a pick'em.
While Odds Shark NFL computer projections don't have the game as a blowout, San Francisco is seen as a clear favorite, winning the game 28 to 23.5.
This would coincide with recent history between these two teams as San Francisco is 8-1 SU and 7-2 ATS in its last nine games against the Cardinals. The projected total of 51.5 would go well OVER the posted total of 42 points in this game.
"Week 17 is always a tough week to handicap because of the various motivations of the teams, some needing a win, some resting starters, some auditioning players for next season," said Jack Randall of OddsShark.com.
"For bubble teams like the Chargers, who we still have a bet on the Super Bowl from Week 1, their motivation may change during Sunday because if early teams win, then they will be eliminated before their game starts."
According to the computer picks, one of the biggest values on the board this week could be the Kansas City Chiefs visiting the San Diego Chargers. Kansas City is a 9.5-point underdog at the betting window, but the computers are picking the Chiefs to win the game outright by a score of 29.1 to 24.
This is another game projected to go comfortably over the total of 44.5 with a combined score of 53.1.
The line was finally set on the Packers Bears matchup after Aaron Rodgers was declared fit to play. The Packers are picked to win by a point, but need to cover 2.5 points.
The New Orleans Saints have been virtually perfect at home this season, going 7-0 SU and 6-0-1 ATS, and are one more home win away from clinching a playoff spot hosting the Tampa Bay Buccaneers this week.
Computer projections have New Orleans winning this game by a score of 24.9 to 15, which would give the Saints their first home ATS loss of the season as they are favored to win by 12.5.
The Seattle Seahawks had a 15-game home winning streak snapped last week by the Arizona Cardinals, losing as an 8-point favorite at home. Seattle will try to bounce back this week and lock up the top seed in the NFC with a home win over the St. Louis Rams.
The projection for this game is right in line with the spread, as Seattle is picked to win 30.2 to 20 as an 11-point home favorite.
The Denver Broncos are also looking to lock up their conference's top seed as an 11.5-point favorite on the road against the Oakland Raiders. They are projected to win and cover by a score of 37.5 to 19.1.
See all the Week 17 NFL picks here.