Cincinnati won the most recent game in the series, and was a five-point favorite at most sportsbooks monitored by Odds Shark to win this one, as well.
It has been a strange month for the Indianapolis Colts and for the NFL betting lines on their games. After starting the season off 6-2 SU and 5-3 ATS with wins over San Francisco, Seattle and Denver, the Colts were looking like a legitimate Super Bowl contender.
But recent blowout losses to the St. Louis Rams and Arizona Cardinals have quieted some of that first-half buzz. A pair of close wins against the Tennessee Titans didn't do much to regenerate that buzz, but a road win over Cincinnati might.
Ranking fifth in the NFL in scoring defense (18 points per game) and sixth in total defense (314.8 yards per game), the Cincinnati Bengals have had a consistently strong season with a 7-4-1 ATS record to go along with their 8-4 SU record.
The Bengals hit a midseason snag with back-to-back losses to Miami and Baltimore, but quickly righted the ship with recent back-to-back wins over Cleveland and San Diego.
Both teams are in virtually identical situations in the standings. Comfortably in the lead in their respective divisions, the focus is now on closing out those division races strong and trying to earn a first-round bye down the stretch. Whichever team wins will be taking a step in the right direction on those fronts.
The Bengals has struggled to a 2-6 ATS mark at home against Indy since 1989.
If both teams play to their potential, this will be a great game between two of the up-and-coming teams in the NFL. The problem is that Indianapolis hasn't looked great in a game since beating Denver back in October.
Perhaps playing a quality opponent like Cincinnati will bring out the best in Andrew Luck and the Colts, but the Bengals seem like the more trustworthy option.
Week 14 Pick: Cincinnati -5.5 | Computer Prediction: 26-21 Bengals | Twitter updates