They are the only remaining team without a Super Bowl victory but oddsmakers don't believe that situation will survive this NFL season.
The Seattle Seahawks are the current favorite on Super Bowl betting odds menus ahead of the conference championship weekend.
The NFC West champs are +200 on 2014 Super Bowl odds at Topbet.eu, slightly ahead of Denver at +210. San Francisco is currently +300 and New England is a relative long shot at +400.
Seattle played in Super Bowl XL, losing 21-10 to Pittsburgh. They host division-rival San Francisco Sunday as a 3.5-point favorite.
In the AFC Championship Game, Tom Brady and Peyton Manning clash for the 15th time. Denver was a midweek 4.5-point favorite over the New England Patriots.
Bettors have been throwing money behind the Pats and 49ers here as road teams have been great bets in recent at this time of year. The roadies are 6-2 ATS in the past four Conference Championship weekends.
Conference Championship Game Betting Trends
San Francisco +3.5 at Seattle, total 39.5
Niners have won three straight playoff road games
Seahawks won six straight playoff home games
Seahawks have played five straight UNDERs when favored
Seahawks are 21-3 SU past 24 games as favorites
UNDER is 6-1 past seven Seahawks games vs. NFC West foes
49ers won five straight vs. NFC West foes (4-1 ATS)
Seattle is 8-2 ATS past 10 at home to San Francisco
New England +4.5 at Denver, total 55
Home team has won and covered three playoff meetings of these teams
Past four meetings played OVER the total
Patriots are 5-1 SU and ATS past six vs Broncos
Patriots are 2-7 ATS past nine road games
Patriots are 7-2 ATS past nine games as underdogs
Broncos have played four straight UNDERs
Denver is 8-3 ATS past 11 games overall
Broncos are 2-7 ATS past nine playoff games
Patriots are 3-9 ATS past 12 playoff games