Bet on Michigan State vs Harvard, UConn vs Villanova odds Saturday

Michigan State and Villanova are both favored in East Region betting. Harvard and UConn will be the victim if odds makers have these handicapped correctly.

SB Nation 2014 NCAA March Madness Coverage

Michigan State is reaching top form at the right time with a 5-1 SU and 6-0 ATS record in its last six games.

The 4-seed Spartans are a 7-point favorite Saturday against 12-seed Harvard. Wrapping up the night's East Region action is Connecticut vs. Villanova, with Villanova going off as a 3.5-point favorite

With Thursday's 93-78 win over Delaware as a 14-point favorite, Michigan State improved to 6-1 SU and ATS in its last seven games as a betting favorite. The Spartans have played in nine second-round games since 2001 and are 7-2 ATS over that stretch.

[ Score predictions, trends and live odds for every March Madness game Saturday]

Michigan State vs. Harvard betting gets underway at 8:40pm ET at the Spokane Arena. Saturday's NCAA Tournament betting card wraps up in Buffalo with Connecticut vs. Villanova odds action at 9:40pm.

Michigan State has won its last four games by an average of 13.3 points per game.

Harvard extended its winning streak to nine games Thursday with its 61-57 upset win over Cincinnati. The Crimson are now 7-1 ATS over their last eight games and 12-seeds overall are 6-1 ATS in their last seven games against 4-seeds in the tournament.

The UNDER is 9-2 in Harvard's last six games as an underdog.

Connecticut improved to 3-1 SU and ATS over its last four games with an 89-81 win over Saint Joseph's. It was a rare offensive shootout for the Huskies, who are 13-2 on the UNDER over their last four games. UConn is 6-2 ATS over its last eight NCAA Tournament games. 7-seeds are 0-10 SU in their last 10 games against 2-seeds.

Villanova cruised to a 73-53 win as a 16.5-point favorite against Milwaukee in the Round of 64 The Wildcats improved to 11-1 SU and 9-3 ATS in their last 12 games as the betting favorite. In their last 12 games against Connecticut, the Villanova Wildcats are 8-2-2 ATS.

The UNDER is 5-1-1 in Villanova's last seven games.

See the latest March Madness odds, matchup reports and trends on every game and follow live lines and your bracket picks with the free odds app.

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