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Universidad de Chile don't appear likely to defend their Copa Sudamericana title. They had an absolute nightmare of a match at home against Sao Paulo on Wednesday.
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Universidad de Chile are going to end their title defense with a whimper after Sao Paulo took them apart on Wednesday night.
Gremio and Millonairos will both be pleased with the result of Tuesday's match, and both will feel like they have a good chance to win the tie in Colombia.
Universidad de Chile are gunning to repeat as Sudamericana champions, while two Brazilian sides and the effective, but hardly entertaining Cerro Porteño stand in their way.