The Italian striker starts with Sergio Aguero just behind as Roberto Mancini rotates his strikers after experimenting with starting with Edin Dzeko in recent weeks. Samir Nasri also starts, as does David Silva, who was an injury doubt for the game.
David de Gea is in goal for Manchester United, with Michael Carrick and Tom Cleverley in midfield. Antonio Valencia returns to the side, but there is no Nemanja Vidic for United. Instead of reverting to a diamond, United stick with a 4-4-1-1 shape, with Rooney just behind Robin van Persie up front.