United have also handed a debut to Alexander Buttner, who replaces Patrice Evra in the Red Devils' lineup, a move that had been speculated in the wake of Evra's continued disappointing form. Meanwhile, Anders Lindegaard continues in goal, while veterans Paul Scholes and Ryan Giggs also surprisingly start, with Shinji Kagawa and Antonio Valencia also taking their place among the substitutes.
Manchester United: Lindegaard, Rafael, Rio, Vidic, Buttner, Nani, Carrick, Scholes, Giggs, Hernandez, Welbeck. Bench: De Gea, Evans, Valencia, RVP, Cleverley, Powell, Kagawa
Wigan Athletic: Al Habsi, Boyce, Caldwell, Figueroa, Ramis, Beausejour, McArthur, McCarthy, Maloney, Di Santo, Kone. Bench: Pollitt, Watson, Crusat, Jones, Gomez, Boselli, Miyaichi