Demba Ba makes his first appearance for the club in the starting lineup, in front of Juan Mata, Eden Hazard and Victor Moses. David Luiz continues in midfield, forming an unconventional double-pivot with Ramires. Ross Turnbull continues in goal in place of the injured Petr Cech.
Southampton meanwhile give starts to James Ward-Prowse, Julio Do Prado and the 17-year-old Luke Shaw. James Rodriguez leads the line up front for the Saints while Artur Boruc continues in goal despite recent nervy displays in the Premier League.
Southampton: Artur Boruc, Jack Cork, Jose Fonte, Maya Yoshida, Luke Shaw, Jason Puncheon, Steven Davis, Morgan Schneiderlin, James Ward-Prowse, Julio Do Prado, James Rodriguez.