Two of the last Champions League campaign's best matches took place between Celtic and Barcelona, who played to 2-1 wins for the home side in each of their group stage encounters. They've been drawn together again this season, but Celtic won't have Victor Wanyama at the heart of their midfield during this year's match at Parkhead.
In what should be the most evenly matched big game of the day, Arsenal host Napoli. The Neapolitans have adjusted well to a new system and life without Edinson Cavani, going unbeaten in all competitions so far this season. Meanwhile, Arsenal are top of the Premier League table, thanks to the addition of Mesut Özil and the incredible form of Aaron Ramsey, who already has eight goals in all competitions.
Schedule (all times ET)
Zenit St. Petersburg vs. Austria Vienna - 12 p.m.
Ajax vs. AC Milan - 2:45 p.m.
Arsenal vs. Napoli - 2:45 p.m.
FC Basel vs. Schalke 04 - 2:45 p.m.
Borussia Dortmund vs. Olympique Marseille - 2:45 p.m.
Celtic vs. Barcelona - 2:45 p.m.
FC Porto vs. Atletico Madrid - 2:45 p.m.
Steaua Bucharest vs. Chelsea - 2:45 p.m.