Panama fast a must win game as they simultaneously hope that Costa Rica can knock off Mexico. Head coach Julio Dely Valdés has made a couple changes to his lineup from Friday that lost against Mexico. Carlos Rodríguez starts at left back, shifting Luis Henríquez to right back replacing Harold Cummings. Up front Román Torres starts alongside Blas Pérez.
Jürgen Klinsmann's side has already clinch the top spot in qualifying and a place in the World Cup so there's little left for them to play for. Brad Guzan takes over in goal for the departed Tim Howard while Clarence Goodson and Michael Orozco take over in the central defense.
Panama (4-4-2): Jaime Penedo; Luis Henríquez, Felipe Baloy, Carlos Rodríguez; Marcos Sánchez, Gabriel Gomez, Amílcar Henríquez, Alberto Quintero; Blas Pérez, Román Torres.