The England winger starts with Mesut Ozil and Olivier Giroud in a front three, while Aaron Ramsey and Jack Wilshere are in midfield in front of Mathieu Flamini. Ignacio Monreal continues at left-back in place of Kieran Gibbs.
Martin Demichelis starts in defence for City meanwhile, partnering Vincent Kompany. Yaya Toure and Fernandinho comprise the midfield, with Sergio Aguero, David Silva and Samir Nasri forming an attacking band of three behind the in-form Alvaro Negredo.
Manchester City starting lineup (4-2-3-1) : Costel Pantilimon; Pablo Zabaleta, Vincent Kompany, Martin Demichelis, Gael Clichy; Fernandinho, Yaya Toure; Samir Nasri, Sergio Aguero, David Silva; Alvaro Negredo
Arsenal starting lineup (4-3-3): Wojciech Szczesny; Bacary Sagna, Per Mertesacker, Laurent Koscielny, Ignacio Monreal; Mathieu Flamini, Aaron Ramsey, Jack Wilshere; Mesut Ozil, Olivier Giroud, Theo Walcott.